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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YWHAB
All Species:
54.24
Human Site:
Y180
Identified Species:
91.79
UniProt:
P31946
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31946
NP_003395.1
246
28082
Y180
A
L
N
F
S
V
F
Y
Y
E
I
L
N
S
P
Chimpanzee
Pan troglodytes
XP_528202
382
42115
Y315
A
L
N
F
S
V
F
Y
Y
E
I
L
N
S
P
Rhesus Macaque
Macaca mulatta
XP_001109676
245
27935
Y179
A
L
N
F
S
V
F
Y
Y
E
I
L
N
S
P
Dog
Lupus familis
XP_852754
244
27832
Y178
A
L
N
F
S
V
F
Y
Y
E
I
L
N
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQV8
246
28068
Y180
A
L
N
F
S
V
F
Y
Y
E
I
L
N
S
P
Rat
Rattus norvegicus
P35213
246
28036
Y180
A
L
N
F
S
V
F
Y
Y
E
I
L
N
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518806
277
31320
Y211
A
L
N
F
S
V
F
Y
Y
E
I
L
N
S
P
Chicken
Gallus gallus
Q5ZLQ6
244
27889
Y178
A
L
N
F
S
V
F
Y
Y
E
I
L
N
S
P
Frog
Xenopus laevis
Q5XHK2
244
27740
Y178
A
L
N
F
S
V
F
Y
Y
E
I
L
N
S
P
Zebra Danio
Brachydanio rerio
Q5PRD0
244
27628
Y178
A
L
N
F
S
V
F
Y
Y
E
I
L
N
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29310
248
28209
Y181
A
L
N
F
S
V
F
Y
Y
E
I
L
N
S
P
Honey Bee
Apis mellifera
XP_391841
247
28058
Y180
A
L
N
F
S
V
F
Y
Y
E
I
L
N
S
P
Nematode Worm
Caenorhab. elegans
Q20655
248
28049
F180
A
L
N
F
S
V
F
F
Y
E
I
L
N
A
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34730
273
31043
Y183
A
L
N
F
S
V
F
Y
Y
E
I
Q
N
S
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.5
99.5
99.1
N.A.
98.7
98.3
N.A.
88.4
97.1
87.4
90.6
N.A.
78.6
80.5
78.2
N.A.
Protein Similarity:
100
60.7
99.5
99.1
N.A.
99.1
98.7
N.A.
88.4
98.7
94.3
96.3
N.A.
89.5
90.2
87.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
100
100
86.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
100
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
59.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
71.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
100
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% E
% Phe:
0
0
0
100
0
0
100
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
100
0
0
0
0
0
0
0
0
0
93
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
100
0
0
0
0
0
0
0
0
0
100
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
100
0
0
0
0
0
0
0
0
86
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
100
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _